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Contracted laboratory for Biomarkers

BIOANALYTICA GENOTYPE SA was established in December 2004 as a biotech startup aiming to provide specialised molecular cytogenetic research and application services to the biomedical Community.

 

Was funded by BIOANALYTICA SA, a leading stakeholder in the greek market for molecular diagnostics and laboratory infrastructure, and by the researcher Dr. Georgia Bardi, Associate Professor of Experimental Clinical Genetics at the Medical school of Lund University, Sweden and former Director of the Cytogenetics facility at Saint Savas Oncology hospital of Athens.

 

Is co-financed by the Greek General Secretariat of Research and Technology under the 3rd Community Support Program (03 Praxe 26).

 

 

SOLID TUMORS

SOLID TUMORS

SOLID TUMORS
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
 Solid Tumor Karyotype Karyotyping Surgical biopsy, FNA, pleural effusion, Ascitic fluid 15
Lung Cancer
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
EGFR:  G719S/C/A (ex18), 28 deletions (ex19), T790M, S768I 7 & 5 insertions (ex20), L858R & L861Q (ex21) PCR-microarrays (CE/IVD) Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 5
EGFR:  G719S/C/A (ex18), 28 deletions (ex19), T790M, S768I 7 & 5 insertions (ex20), L858R & L861Q (ex21) in liquid biopsy PCR-microarrays (CE/IVD) 10ml ολικού Αίματος σε ειδικά σωληνάρια  5
EGFR mutations: exons 18-21  NGS Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 10
EGFR mutations in liquid biopsy: exons 18-21  NGS 10ml peripheral blood in special tubes 10
ALK Rearrangements (2p23) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  10
ROS1 Rearrangements (6q22) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  10
RET Rearrangements (10q11) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  10
MET Amplification (7q31) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  10
Her-2 neu (ΕRΒΒ2) amp(17)(q11) FISH 3 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
BRAF V600E/K, c.1799T>A Real-Time PCR Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 3
BRAF V600E/K, c.1799T>A in liquid biopsy  Real-Time PCR 10ml peripheral blood in special tubes 5
FGFR1 Amplification (8p11) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  10
KRAS: codons 12 & 13 (ex 2) - codons 59 & 61 (ex 3) - codons 117 & 146 (ex 4) PCR-microarrays (CE/IVD) Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 5
KRAS: codons 12 & 13 (ex 2) - codons 59 & 61 (ex 3) - codons 117 & 146 (ex 4) in liquid biopsy PCR-microarrays (CE/IVD) 10ml peripheral blood in special tubes 5
KRAS/NRAS (exons 2,3,4,5 &2,3,4) and BRAF  (exons 1-18 ) NGS Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 10
KRAS/NRAS (exons 2,3,4,5 &2,3,4) and BRAF  (exons 1-18) in liquid biopsy  NGS 10ml peripheral blood in special tubes 10
SALIVARY GLAND CANCER: Mucoepidermoid carcinoma
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
t(11;19)(q21;p13.1) MAML2/CRTC1  FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
GASTROINTESTINAL SYSTEM
Colorectal cancer
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
BRAF V600E/K, c.1799T>A Real-Time PCR Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 3
BRAF (ALL MUTATIONS) NGS Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 10
UGT1A1 Fragment Analysis  3-5ml of blood in EDTA tube 3
KRAS/NRAS (exons 2,3,4,5 & 2,3,4) and BRAF  (exons 1-18 ) NGS Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 10
MicroSatellite Instability (MSI) Fragment Analysis Tissue biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm & 3-5ml of blood in EDTA tube 5
Hereditary nonpolyposis colorectal cancer (HNPCC) - Lynch Syndrome
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
MicroSatellite Instability (MSI) Fragment Analysis Tissue biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm & 3-5ml of blood in EDTA tube 5
MLH1, MSH2, MSH6, PSM2, EPCAM NGS  3-5ml of blood in EDTA tube 10
BRAF V600E/K  Real-Time PCR Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 3
Familial adenomatous polyposis (FAP)
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
APC MLPA  3-5ml of blood in EDTA tube 5
APC + MUTYH NGS  3-5ml of blood in EDTA tube 10
Gastric cancer
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
Her-2 neu (ΕRΒΒ2) amp(17)(q11) FISH 3 slides of paraffin embedded tissue slides of 4μm  7
Barrett´s Esophagus / oesophageal adenocarcinoma
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
MYC(8q24), p16(9p21), her-2 (17q12), ZNF217 (20q13) FISH Sample collected during endoscopy, before biopsy, in PreservCyt fixative  10
Gastrointestinal stromal tumors (GIST) 
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
c-Kit (all exons, including 9, 11, 13, 17) / PDGFRA (all exons, including 12, 14, 18) NGS Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 10
Familial Pancreatitis
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
Pancreatitis 5 genes  CFTR, CPA1, CTRC, PRSS1, SPINK1 NGS  3-5ml of blood in EDTA tube 30
Pancreatitis 3 genes  PRSS1, SPINK1, CFTR                             MLPA  3-5ml of blood in EDTA tube 40
Pancreatic cancer
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
PALB2 gene  Full Sequencing   3-5ml of blood in EDTA tube 20
PALB2 gene  MLPA  3-5ml of blood in EDTA tube 20
SMAD4 gene- Somatic mutations NGS Tissue biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm & 3-5ml of blood in EDTA tube 15
BREAST/OVARIAN CANCER
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
Her-2 neu (ΕRΒΒ2) amp(17)(q11) FISH 3 slides of paraffin embedded tissue slides of 4μm  7
BRCA1&2 Somatic mutations  NGS  6-8 slides of paraffin embedded tissue slides of 10μm & 5-10ml of blood in EDTA tube 10
AKT1 full sequencing   Sequencing   3-5ml of blood in EDTA tube 20
AKT1 deletion/duplication   MLPA  3-5ml of blood in EDTA tube 60
BRCA1&2 (DELETIONS/DUPLICATIONS) MLPA  3-5ml of blood in EDTA tube 20
BRCA1&2 Inherited mutations NGS 5-10ml of blood in EDTA tube 10
BRCA1&2 Inherited mutations  + ΜLPA (DELETIONS/DUPLICATIONS) NGS + MLPA 5-10ml of blood in EDTA tube 10
BREAST CANCER PANEL (26 GENES) NGS 5-10ml of blood in EDTA tube 20
TP53 somatic mutations full sequencing   NGS  3-5ml of blood in EDTA tube 10
TP53 deletions  MLPA  3-5ml of blood in EDTA tube 10
TP53 full sequencing + deletion/duplication  NGS + MLPA 5-10ml of blood in EDTA tube 10
CERVICAL CANCER
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
hTERC amp(3)(q26), c-MYC amp(8)(q24), CEP7 FISH  6 slides of formalin fixed paraffin embedded tissue sections of 4μm,  10
HPV Typing & Genotyping PCR-microarrays (CE/IVD) Cell suspension or paraffine embedded tissue, 15-25°C  3
ENDOMETRIAL SARCOMA
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
JAZF1/SUZ12  t(7;17)(p15;q21) FISH  4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  10
PROSTATE CANCER
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
PCA 3 RT-PCR 5-10 ml of urine fixed in fixative fluid  2
TMPRSS2-ERG (21q22.3-21q22.2) FISH  4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
BLADDER CANCER
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
UROVYSION Aneuplpoidies 3, 7, 17 and 9p21 FISH 35ml of urine (2:1) in preservative fluid 7
KIDNEY CANCER
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
Trisomy 7 & Trisomy 17  FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
TFE3, Xp11.2 (all reclassifications)
t(X;1)(p11.2;q21) TFE3
FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
THYROID CANCER
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
BRAF V600E/K Real-Time PCR Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 3
BRAF (all exons, including exons 11, 15) NGS Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 10
APC, PTEN, RET genes - heredited mutation NGS 3-5ml of blood in EDTA tube 15-25°C 20
APC, PTEN, RET genes - heredited mutations  MLPA 3-5ml of blood in EDTA tube 15-25°C 15
HEAD/NECK CANCER
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
EGFR amp(7)(p12) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  10
SKIN CANCER
Malignant melanoma
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
BRAF V600E/K Real-Time PCR Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 3
BRAF (all exons including exons 11,15) NGS Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 10
NRAS (exon 2: codons 12 /13) Pyrosequencing Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 5
c-Kit (all exons, including 9, 11, 13, 17) / PDGFRA (all exons, including 12, 14, 18) NGS Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 10
RREB1 (6p25), MYB (6q23), CEP6, CCND1 (11q13) 4xFISH 8 slides of formalin fixed paraffin embedded tissue sections of 4μm,  10
NEUROGENIC TUMORS
Neuroblastoma 
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
N-MYC AMPLIFICATION (2p24) MLPA Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 5
N-MYC AMPLIFICATION (2p24) Real-Time PCR Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 5
 amp N-MYC/2p24, deletion 1p36, deletion 11q, gain 17q MLPA Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 5
N-MYC AMPLIFICATION (2p24) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
1p36 Deletion FISH 8 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
11q Deletion FISH 8 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
17q Gain FISH 8 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
 amp N-MYC/2p24, deletion 1p36, deletion 11q, gain 17q FISH 8 slides of formalin fixed paraffin embedded tissue sections of 4μm,  10
Myeloblastoma
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
i(17)(q10) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
Glioma/ Oligodendroglioma
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
1p/19q deletion  FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
EGFR FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  10
MGMT hypermethylation Pyrosequencing 6 slides of formalin fixed paraffin embedded tissue sections of 4μm,  5
SOFT TISSUE TUMORS 
LIPOMAS
Well differentiated liposarcomas
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
12q14-15 (MDM2) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  10
Myxoid liposarcoma
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
FUS-DD1T3(CHOP) t(12;16)(q13;p11) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
EWSR1-DD1T3(CHOP) t(12;22)(q13;q12 FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
DDIT3(CHOP) /12q13, all reclassifications, t(12;16)(q13;p11), t(12;22)(q13;q12), t(12;20;22)(q13;q11;q12)  FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
FIBROBLAST/MYOBLASTIC TUMORS
Desmoid-type fibromatosis (DTF)
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
Trisomy  8 FISH CE/IVD 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
Trisomy  20 FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
-5q21 FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
APC NGS Surgical biopsy/ 6-8 slides of paraffin embedded tissue sections of 10μm/  3-5ml of blood in EDTA tube,  15-25°C 10
Inflammatory myoblastic tumors
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
TPM3-ALK t(1;2)(q25;p23) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
TPM4-ALK t(2;19)(p23;p13) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
CTLC-ALK t(2;17)(p23;q23) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
RANBP2-ALK t(2;2)(p23;q13) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
CARS-ALK t(2;11)(p23;p15) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
ATIC-ALK inv(2)(p23;q35) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
Dermatofibrosarcoma protuberans/ Giant cell fibroblastoma  
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
COL1A1-PDGFB, t(17;22)(q22;q13) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
Neonatal fibrosarcoma / Congenital mesoblastic nephroma 
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
ETV6-NTRK3 t(12;15)(p13;q25) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
Low differentiation fibromyalgia sarcoma 
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
     FUS-CREB3L2 t(7;16)(q33;p11) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
     FUS-CREB3L1 t(11;16)(p11;p11) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
 STRIATED SKELETAL MUSCLE TUMORS
Rhabdomyosarcoma (alveolar)
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
PAX7-FOXO1(FKHR) /t(1;13)(p36;q14) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
PAX7-FOXO1(FKHR) /t(1;13)(p36;q14) Real-Time PCR  0.2cm³ surgical biopsy in sterile tube with 3-5ml saline, 4°C 5
PAX3-FOXO1(FKHR) /t(2;13)(q37;q14) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
PAX3-FOXO1(FKHR) /t(2;13)(q37;q14) Real-Time PCR  0.2cm³ surgical biopsy in sterile tube with 3-5ml saline, 4°C 5
UNSPECIFIED DIFFERENTIATED TUMORS 
Ovarian sarcoma
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
SS18(SYT)-SSX1 & SSX2 Real-Time PCR  0.2cm³ surgical biopsy in sterile tube with 3-5ml saline, 4°C 5
SS18 (SYT) /18q11.2, all reclassifications, t(X;18)(p11.2;q11.2) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
Desmoplastic mircro-round cell tumors
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
EWSR1-WT1 t(11;22)(p13;q11-13)  FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
EWSR1-WT1 t(11;22)(p13;q11-13)  Real-Time PCR  0.2cm³ surgical biopsy in sterile tube with 3-5ml saline, 4°C 5
Intercellular sarcoma
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
EWSR1 (22q12), all reclassifications FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
Extraskeletal myxoid chondrosarcomas
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
EWSR1 (22q12), all reclassifications FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
EWSR1-NR4A3 t(9;22)(q22;q12)
TAF2N-
NR4A3 t(9;17)(q22;q11)
TCF12-
NR4A3 t(9;15)(q22;q21)
TFG-
NR4A3 t(3;9)(q11;q22)
FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
Alveolar Soft Part Sarcoma (ASPS)
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
ASPL-TFE3 t(X;17)(p11;q25) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
Angiomatoid fibrous histiocytoma
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
EWSR1-ATF1 t(12;22)q(13;q12)
EWSR1-CREB1 t(2;22)(q33;q12)
FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
FUS-ATF1 t(12;16)(q13;p11) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
Extra-muscular myoepithelial tumors
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
EWSR1 (22q12), all reclassifications FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
BONE TUMORS 
ROUND CELL TUMORS 
Ewing sarcoma/ Primitive neuroectodermal  tumors (blue microtubule cell tumors)
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
EWSR1 (22q12), all reclassifications FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
EWSR1-FLI/ERG/ETV Real-Τime PCR  0.2cm³ tissue from surgical biopsy in a sterile tube with 3-5ml saline, 4°C 5
EWSR1-FLI/ERG RT-PCR Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm 5
EWSR1-FLI, t(11;22)(q24;q12) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
EWSR1-ERG, t(21;22)(q22;q12) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
EWSR1-ERG Real-Τime PCR 250mm³ Tissue Biopsy 5
EWSR1-ETV1 Real-Τime PCR 250mm³ Tissue Biopsy 5
EWSR1- ETV1 t(7;22)(p22;q12)
EWSR1-FEV t(2;22)(q33-35;q12)
EWSR1-E1AF(ETV4) t(17;22)(q21;q12)
EWSR1-ZSG(PATZ1) inv(22)(q12q12)
FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
FUS-ERG t(16;21)(p11;q22) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm,  7
ONCOLOGY TEST PANELS
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
  OVARIAN/BREAST CANCER
(Pancreas, parathyroid, kidney, endometrium, colon, gastrointestinal) GENES: BRCA1,BRCA2, BARD1,BRIP1, RAD51C,RAD51D,TP53,MRE11A,RAD50,NBN,FAM175A,ATM,PALB2,STK11,MEN1,PTEN,CDH1,MUTYH,CHEK2,BLM,XRCC2,EPCAM,MLH1,MSH6,PMS2, MSH2
NGS 5-10ml of blood in EDTA tube 10
 SOMATIC CA -2
(Glioblastoma, colon, lungs, breastς, ovaries, endometrium, gastrointestinal) GENES: PTEN, EGFR, PIK3CA, ERBB2, PIK3R1
 
NGS 5-10ml of blood in EDTA tube 10
 SOMATIC CA -3
(Glioblastoma, colon, lungs, breastς, ovaries, endometrium, gastrointestinal, etc.) GENES: ΑΚΤ, ALK, BRAF, CDKN2A, CTNNB1, DDR2, EGFR, FGFR2, FGFR3, H3F3A, HIST1H3B, HRAS, KIT, KRAS, MEK1, NRAS, PIK3CA, PTEN, STK11, ERBB2, ERBB4, IDH1, IDH2, PDGFRA, PIK3R1, PIK3CA
 
NGS 5-10ml of blood in EDTA tube 10
56 ONCOLOGY GENE PANEL                                   (ΑΒL1, AKT1, ALK, APC, ATM, BRAF, CDH1, CDKN2A, CSF1R, CTNNB1, DDR2, DNMT3A, EGFR, ERBB2, ERBB4, EZH2, FBXW7, FGFR1, FGFR2, FGFR3, FLT3, FOXL2, GNA11, GNAQ, GNAS, HNF1A, HRAS, UDH1, IDH2, JAK2, JAK3, KDR, KIT, KRAS, MAP2K1, MET, MLH1, MPL, MSH6, NOTCH1, NPM1, NRAS, PDGFRA, PIK3CA, PTEN, PTPN11, RB1, RET, STK11, SMAD4, SMARCB1, SMO, SRC, TP53, TSC1, VHL)   NGS Surgical biopsy/ 6-8 slides of paraffin embedded tissue slides of 10μm/10 mL blood in Streck tubes 10
LUNG CANCER
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
KRAS/NRAS/BRAF (all mutations)  NGS Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 10 
KRAS/NRAS (all mutations) and BRAF (EXON 15) NGS Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 10 
GASTROINTESTINAL SYSTEM
Colorectal Cancer
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
KRAS/NRAS/BRAF (all mutations)  NGS Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 10 
KRAS/NRAS (all mutations) and BRAF (EXON 15) NGS Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 10 
Gastrointestinal Stromal Tumors (GISTs)
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
c-KIT/PDGFRA (all mutations) NGS Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 10
BREAST/OVARIAN CANCER
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
BRCA1&2 NGS  5-10 mL of blood in EDTA tube  10 
BRCA1&2 + ΜLPA (deletions/duplications) NGS  5-10 mL of blood in EDTA tube  10 
BRCA 1 & 2 SOMATIC MUTATIONS (PARPi TREATMENT) NGS  5-10 mL of blood in EDTA tube  10 

Analysis of the most frequently mutated genes associated with breast/ovarian cancer (26 genes: BRCA1,BRCA2, BARD1, BRIP1, D51C, RAD51D, TP53, MRE11A, RAD50, NBN,FAM175A,ATM,PALB2,STK11,MEN1,PTEN,CDH1,MUTYH,CHEK2,BLM,XRCC2,EP
NGS  5-10 mL of blood in EDTA tube  20 
p53 full sequencing   NGS  3-5 mL of blood in EDTA tube 10 
p53 deletion/duplication   MLPA  3-5 mL of blood in EDTA tube 10 
p53 full sequencing + deletion/duplication  NGS + MLPA  5-10 mL of blood in EDTA tube  10 

BioAnalytica-Genotype SA serves the healthcare market by offering Cytogenetics and Molecular Genetics tests, designed to answer questions related to diagnosis, prognosis and therapy selection for hematologic and solid tumor cancers.