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Contracted laboratory for Biomarkers

BIOANALYTICA GENOTYPE SA was established in December 2004 as a biotech startup aiming to provide specialised molecular cytogenetic research and application services to the biomedical Community.

 

Was funded by BIOANALYTICA SA, a leading stakeholder in the greek market for molecular diagnostics and laboratory infrastructure, and by the researcher Dr. Georgia Bardi, Associate Professor of Experimental Clinical Genetics at the Medical school of Lund University, Sweden and former Director of the Cytogenetics facility at Saint Savas Oncology hospital of Athens.

 

Is co-financed by the Greek General Secretariat of Research and Technology under the 3rd Community Support Program (03 Praxe 26).

 

 

PHARMACOGENETICS

PHARMACOGENETICS

PHARMACOGENETICS
Test (genetic marker) Method Specimen Type  Turnaround Time (business days) 
Clopidogrel Resistance (PLAVIX) (CYP2C19) Real-Time PCR  3-5mL of blood/bone marrow in EDTA tube 3 
Sensitivity to Azathioprine (TPMT) Real-Time PCR  3-5mL of blood/bone marrow in EDTA tube 3 
Warfarin Resistance (VKOR/CYP2C9) Real-Time PCR  3-5mL of blood/bone marrow in EDTA tube 3 
Response to 5-FLUOROURACIL (5-FU/DPD) PCR-hybridization 3-5mL of blood/bone marrow in EDTA tube 3 
Response to Trastuzumab  (Her2/neu)  FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm 7
Response to Afatinib  (Her2/neu) FISH 4 slides of formalin fixed paraffin embedded tissue sections of 4μm 7
Response to Arsenic Trioxide, PML/RARa detection (bcr1, bcr2, bcr3) Real Time PCR 3-5mL of bone marrow in EDTA tube 1 
Response to Arsenic Trioxide,  PML/RARa  bcr1 quantitative,    t(15;17)(q22;q21) Real Time PCR 3-5mL of bone marrow in EDTA tube 3
Response to Arsenic Trioxide,  PML/RARa  bcr2 quantitative t(15;17)(q22;q21) Real Time PCR 3-5mL of bone marrow in EDTA tube 3 
Response to Arsenic Trioxide, PML/RARa bcr3 quantitative,    t(15;17)(q22;q21) Real Time PCR 3-5mL of bone marrow in EDTA tube 3 
Response to Arsenic Trioxide,  RARa/ 17q21 (various partners) FISH 3-5mL of bone marrow in heparin tube, 15-25°C 5 
Response to Rasburicase   (G6PD)  PCR-RFLPs 3-5mL of blood/bone marrow in EDTA tube 3
Response to Nilotinib (UGT1A1) Fragment Analysis 3-5mL of blood/bone marrow in EDTA tube 3
Response to Nilotinib (Philadelphia) FISH 3-5mL of blood/bone marrow in heparin tube,  15-25°C 5 
Response to Nilotinib (BCR_ABL) Real Time PCR 3-5mL of blood/bone marrow in EDTA tube 5 
Response to Mercaptopurine  (TPMT)  PCR-RFLPs 3-5mL of blood/bone marrow in EDTA tube 3
Response to Lapatinib  (Her2/neu)   FISH 3 slides of formalin fixed paraffin embedded tissue sections of 4μm 7
Response to Irinotecan  (UGT1A1)  Fragment Analysis 3-5mL of blood/bone marrow in EDTA tube 3 
Response to Imatinib mesylate  (PDGFRA/C-KIT)  NGS Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm & 3-5mL of blood in EDTA tube 10 
Response to Gefitinib   (EGFR) Pyrosequencing Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 5
Response to Erlotinib  (EGFR)   Pyrosequencing Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 5 
Response to Dasatinib  (Philadelphia)  FISH 3-5mL of blood/bone marrow in heparin tube, 15-25°C 5 
Response to Dasatinib  (BCR_ABL)  Real Time PCR 3-5ml of blood/bone marrow in EDTA tube  5 
Response to Cetuximab   (Kras/Nras/BRAF)  NGS Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 5 
Response to Cetuximab   (Kras/Nras/BRAF)  Real Time PCR Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 5 
Response to Cetuximab (EGFR)  Pyrosequencing Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 10 
Response to Capecitabine  (DPD) Real-Time PCR  3-5mL of blood/bone marrow in EDTA tube  3
Response to Busulfan   (Philadelphia)   FISH 3-5mL of blood/bone marrow in heparin tube, 15-25°C 5 
Response to Lenalidomide  (5q-)  FISH 3-5mL of blood/bone marrow in heparin tube, 15-25°C 5 
Response to Crizotinib  (ALK)   FISH 4-5 slides of formalin fixed paraffin embedded tissue sections of 4μm 10
Response to Crizotinib  (ROS1)   FISH 4-5 slides of formalin fixed paraffin embedded tissue sections of 4μm 10
Response to Crizotinib  (MET)   FISH 4-5 slides of formalin fixed paraffin embedded tissue sections of 4μm 10
Response to Crizotinib  (ALK/MET/ROS1)   FISH 6 slides of formalin fixed paraffin embedded tissue sections of 4μm 10
Response to Dabrafenib  (BRAF) Real time PCR Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 3
Response to Cabozantinib  (RET)  FISH 2-3 slides of formalin fixed paraffin embedded tissue sections of 4μm 10
MET mutations (exon 14 skipping) RNA sequencing 2-3 slides of formalin fixed paraffin embedded tissue sections of 4μm 10
Response to Olaparib (BRCA1/2)  NGS Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 5 
Response to Olaparib (BRCA1/2)  MLPA Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 5 
Response to Olaparib (BRCA1/2)  NGS + MLPA Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 5 
Response to Thioguanine   (TPMT)  PCR-hybridization Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 5 
Response to Trametinib   (BRAF)  Real Time PCR Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 5 
Response to Vemurafenib   (BRAF)  Real Time PCR Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 5 
Response to anticoagulants   (CYP2C19)  PCR-hybridization Tissue biopsy/6-8 slides of paraffin embedded tissue sections of 10μm 5 
Response to IFN therapy   (IL28b genotypes))  Real Time PCR 3-5mL of blood, 15-25°C 5 

BioAnalytica-Genotype SA serves the healthcare market by offering Cytogenetics and Molecular Genetics tests, designed to answer questions related to diagnosis, prognosis and therapy selection for hematologic and solid tumor cancers.